Amendments to IBC Applications

Submit an amendment when making changes to experimental protocols, adding new infectious agents/r/sNA molecules/ biological toxins, moving to a new research space, or making other changes that might alter the biosafety risks associated with the protocol.

In addition, amendments should be used to report changes to laboratory staff, new sources of funding, and changes or additions of titles.

Most changes to experimental procedures will require full committee review. Changes in funding, personnel, and updating biosafety cabinet dates are reviewed administratively.

To request IBC approval for changes in experimental activities:

• Submit an amendment in eProtocol. See the Create Amendments job aid.
• Your submission should include changes in the eProtocol application as well as the inclusion of updated attachments reflecting the requested changes in experimental procedures.
• New experimental procedures should not begin until we have approved the amendment. An approval letter will be sent via email once approved for your records.

To change or add titles to a protocol already approved by the IBC:

• Submit an amendment in eProtocol. See the Create Amendments job aid.
• A title can be added or changed in the "Study Objectives" section. 
• Please note that Sponsored Projects Administration (SPA) verifies funding based on the information in the Funding section of the application rather than by the Study Title.
• If this is the only requested change, an approval letter will not be sent unless requested. You may check the status of the amendment in eProtocol to confirm approval.

To add a new funding source to a protocol:

• Submit an amendment in eProtocol. See the Create Amendments job aid.
• A new funding source can be added through the “Funding” section of an amendment. Sponsored Projects Administration (SPA) tracks funding and IBC approval through this section of eProtocol.
• Note: Sometimes when searching for sponsored projects the first/default option results in a message reporting “application server is down.” Instead, use the second option (Search for Proposal(s)/Sponsored Project Award(s) awarded to another Principal Investigator) and enter the PI’s name or User ID to search.
• If this is the only requested change, an approval letter will not be sent unless requested. You may check the status of the amendment in eProtocol to confirm approval.

To change the personnel in an approved IBC protocol:

• Submit an amendment in eProtocol. See the Create Amendments job aid.
• Review the eProtocol Roles section of our website for more details on the various eProtocol actions the different personnel roles can make.
• Ensure new personnel have completed the appropriate online training courses.
• New personnel should not begin work on IBC related activities until the amendment has been approved.
• If this is the only requested change, an approval letter will not be sent unless requested. You may check the status of the amendment in eProtocol to confirm approval.