Monoclonal Antibodies
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The following Monoclonal Antibodies are currently available for Express Licensing through the University of Minnesota. The University may have other monoclonals available through standard licensing. Please contact otcagree@umn.edu to inquire about antibodies not available through Express Licensing.
The antibodies are listed by creator. If you would like to license any of these antibodies, please complete the University of Minnesota Express License Agreement.
Tucker W. LeBien, Ph.D.
• TA-1 recognizing CD11a (LeBien TW et al. A monoclonal antibody (TA-1) reactive with human T lymphocytes and monocytes. J Immunol. 25:2208, 1980.) learn more
• BA-1 recognizing CD24 (Abramson CS et al. A monoclonal antibody (BA-1) reactive with cells of human B lymphocyte lineage. J Immunol. 126:83, 1981.) learn more
• EA-5 and BE-1 recognizing CD40 (Law CL et al. Analysis of expression and function of CD40 on normal and leukemic human B cell precursors. Leukemia. 4:732, 1990.)
learn more
Ronald R. Jemmerson, Ph.D.
• 7H8.2C12 (y2b,k)– produces mouse monoclonal antibody (mAb) reactive with non-native form of cytochrome c (CYT), specific for the carboxyl terminal dodecapeptide; useful for Western blots of CYT from many species (e.g. mouse, human, rat, horse, cow, drosophila, frog, maize, etc.). (Ref: Jemmerson R, et al., Eur.J. Immunol., 1991, 21: 143-151; Goshorn S, et al., J Biol Chem, 1991, 266: 2134-2142; Liu X, et al., Cell 1996, 86: 147-157.)
• 6H2.B4 (y1,k) –produces mouse mAb reactive with native form of CYT in the vicinity of residue 62; useful for immunoprecipitation of CYT from mouse, rat, human, and possibly some other species; useful for immunofluorescence detection of CYT in some cells (Ref: Goshorn S, et al., J Biol Chem, 1991, 266: 2134-2142; Liu X, et al., Cell 1996, 86: 147-157; Srinivasan A, et al., J Biol Chem 1998, 273: 4523-4529.)
• 2.7D5 (y2a,k) – produces mouse mAb reactive with native CYT; useful for detection of CYT in situ (by immunofluorescence of permeabilized cells from various species (e.g. mouse, rat, human, and possibly some others) and for immunoprecipitation; Specific for the region around residue 62 on pigeon CYT and cross-reacts with mouse/rat and human CYT. (Ref: Jemmerson R, et al., Biochem, 1999, 38: 3599-3609.
• 2B5 (y2a,k) – produces mouse mAb reactive with native CYT in the vicinity of residue 44; useful for detection of CYT in situ by immunofluorescence of permeabilized cells of human origin, also reacts with CYT from some other species (e.g. cow, horse, dog) and useful for immunoprecipitation; Anti-horse CYT, cross reactive with human and horse cytochrome C. (Ref: Goshorn S, et al., J Biol Chem, 1991, 266: 2134-2142.)
• 2G8.B6 (y1,k)– Hybridoma clone secreting mAb elicited against mouse/rat CYT, which also cross reacts with human CYT, amino acid residues in the vicinity of residue 62; detects altered conformation of drosophila CYT in pre-apoptotic cells; immunofluorescence and immunoprecipitation (Ref: Mueller CM and R Jemmerson, J Immunol, 1996, 157: 5329-5338; Varkey J et al., J Cell Biol, 1999, 144: 701-710.)
• IE8 (y1,k)– produces mAB specific for the region around residue 62 on mouse/rat CYT and cross-reacts with human CYT. (Ref: Minnerath JM, et al., Eur J Immunol, 1995, 25: 784-791.)
• 1G1.E9 (y1,k)– produces anti-horse CYT mAb, cross reactive with human and murine CYT in the vicinity or residue 44; immunofluorescence and immunoprecipitation. (Ref: Goshorn S, et al., J Biol Chem, 1991, 266: 2134-2142.)
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• Anti-ß1 Integrins
o P4G11 ß1 (activates, epitope 305-354)
o P5D2 ß1 (inhibits, binds epitope 207-218)
o P1H4 a4 (inhibits a4 function, binds epitope B)
• Anti-aV Integrins
o P8G8 av
o P1F6 avß5 (inhibits)
• Anti-Selectins
o P2H3 E-selectin (inhibits)
o P8G6 P-selectin
• Anti-CAMS
o P2A4 ICAM (inhibits)
o P8B1 VCAM (inhibits, epitope 2)
o P3C4 VCAM (inhibits, epitope 1)
o P2B1 PECAM (activates ß1 adhesion of T cells to endothelial cells)
o P3D1 endoglin
o P4A4 endoglin
o P1H12 endothelial specific marker*
*can be used to identify circulating endothelial cells (Solovey, et al.,
NEJM., 337: 1585-1590, 1997)
• Anti laminin 5
o P3H9-2 laminin-5 (inhibits certain binding)
o P3E4 laminin-5
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Send completed License with License Fee to:
University of Minnesota
Office for Technology Commercialization
Attention: Express Licensing
1000 Westgate Drive
Suite 160
Saint Paul MN 55114-8653
Any modifications to the License terms are subject to the current Agreement Modification Fee of the University of Minnesota.
Licenses without payment included will be returned to the proposed licensee.
If your institution requires a purchase order or other means of payment,
please e-mail otcagree@umn.edu.
Any modifications to the License terms are subject to the current Agreement Modification Fee of the University of Minnesota.
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mAb License Agreement |