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Download forms to apply for approval to use animals at the University.

Training and Certification

How to become certified to work animals at the University, training requirements.


Animal Use Policies & Guidelines

Policies, guidelines, recordkeeping forms, federal and University regulations.


eProtocol provides a common tool for principal investigators, IACUC staff and committee members to submit, review and communicate about protocols. Access is available to anyone with an x.500 user name and password.  All staff listed as working on a protocol can view the protocol details via the eProtocol system.

For more information visit:

View the short instructional video:



Grant Documents: AAALAC Accreditation Letter, NIH Assurance Information, and USDA Registration Number

1. AAALAC Accreditation Letter - For use when funding agencies request a copy of the most recent UMN AAALAC accreditation letter. Note: AAALAC accreditation applies only to facilities in the AHC, CLA, and the Hormel Institute.

2. The UMN's NIH Animal Welfare Assurance Number is A3456-01. Most recent renewal date: 4/5/16. Expiration date: 4/30/20. This applies to all UMN animal activities funded by the Public Health Service.

3. The UMN's USDA Registration Number is 41-R-0005. This applies to all UMN animal activities regulated by the USDA. Both the species of animal and the nature of the activity determines USDA regulation.

12/12 updated 4/2016



Guide for the Care and Use of Laboratory Animals (The Guide) 8th edition, 2011



NIH Vertebrate Animal Section Template


"Simplification of the Vertebrate Animals Section

NIH has simplified the Vertebrate Animals Section (VAS) of grant applications, cooperative agreements, and contract proposals to remove redundancy with IACUC review while meeting the requirements of the PHS Policy. Changes include:

·         Guidance on criteria to be addressed has been updated

·         Description of veterinary care is no longer required

·         Justification for the number of animals has been eliminated

·         Description and justification of the method of euthanasia is required only if the method is not consistent with AVMA Guidelines for the Euthanasia of Animals


See NIH Guide Notice NOT-OD-16-006 to learn more about the updated VAS requirements, the implementation schedule, and what has changed. See also, the Vertebrate Animals Section webpage – a new resource where you can find more information on the requirements, a checklist, detailed instructions plus links to worksheets."

To assist University of Minnesota investigators who house animals in Research Animal Resources with the writing of the VAS of NIH grant proposals, a document with suggested language and advice on completing the VAS has been developed. You can view/download that document HERE.

If you have additional questions about completing the VAS, please contact the Institutional Veterinarian, Dr. Mark Suckow, at

3/08/10, updated 10/14/15


ARRIVE Guidelines Checklist

The National Centre for the Replacement, Refinement & Reduction of Animals in Research has published the following help aid to assist in writing manuscripts that report research with animals for publication in scientific journals.  These guidelines and other help aids regarding ethical use of animals in scientific research can be found at the website:

Please contact the IACUC office ( if you would like assistance in addressing any of the items listed within their guidelines regarding institutional standards for housing and husbandry.



Building Flexibility into Animal Care and Use Protocols  

In order to maintain compliance and the flexibility needed in the conduct of animal studies, it is recommended that ACUP forms be written with a range of justifiable options to use.  For example, when stating the method of euthanasia, indicate several acceptable options (eg. carbon dioxide or pentobarbital overdose). You may cut and paste standard euthanasia methods from the RAR website HERE. Do the same for anesthetic regimens (eg. ketamine/xylazine or isoflurane).  For blood collection, give a range of acceptable amounts, frequency and intervals (eg. 0.05-0.10 ul of blood will be drawn from either the tail vein or the facial vein every 1 to 3 days for no more than 14 days).  For study endpoints, give maximum times or markers (eg. animals will be euthanized no later than 3 weeks after administration of test article depending on animal condition and study progress).  For behavioral tests or radiographic examinations, give a range of timing and frequency (eg. an x-ray will be taken 2-6 times during the 10-30 days following the procedure).   The flexible options you build into an ACUP should be based in appropriate study design and reasonable choices, but careful planning at the time of ACUP completion can help minimize the need for protocol amendments in the future.  

11/05/09 rev 9/28/10




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